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In recent years, the establishment of cross-tissue single-cell atlases has systematically revealed the lineage and functional heterogeneity of human monocytes/macrophages in health and disease, providing an important reference framework for analyzing metabolism-phenotype coupling at the human level (135)

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Therefore, in the setting of a degenerative meniscal tear with osteoarthritis, the patient and doctor also need to discuss treatment alternatives for the arthritis such as injections into the knee or partial or total knee replacement