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If a person has more severe obesity and loses weight very, very quickly, there's a possibility that the rapid weight loss may cause them to have gallstones, says Vash

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The biology predicted the outcome before the studies confirmed it

Some users report mild appetite changes or perceived energy shifts both of which are non-specific and could be placebo or could indicate partial absorption that's not been formally characterized

Appendix: Sources and Further Reading Primary Scientific Publications Eng J, Kleinman WA, Singh L, Singh G, Raufman JP