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Taking a proton pump inhibitor or other medications that reduce stomach acid for reflux or ulcers, as well as taking metformin for diabetes, can reduce absorption of B12 in food or supplements

Peptides begin degrading immediately when exposed to water

Any claims about synergistic fat-loss effects from combining these agents are not supported by peer-reviewed clinical evidence

Delivery Methods: At our clinic, we find that B12 injections (often utilizing hydroxocobalamin or methylcobalamin) bypass the digestive system entirely

Nevertheless, ongoing surveillance and research are important to fully characterize long-term safety as use of this therapy expands