Zofran, in combination with a specific class of antidepressants known as serotonin reuptake inhibitors (SSRIs) , can cause serotonin syndrome to occur
Availability can vary, and a specific formulation is not guaranteed
Clin Gastroenterol Hepatol 6(6):635643.e1 Szayna M, Doyle ME, Betkey JA, Holloway HW, Spencer RG, Greig NH et al (2000) Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
Whether such a POMC effect contributes to the increased mRNA of the steroidogenic enzymes that we found in the septic mice, and thus to the elevated plasma CORT while ACTH is not increased and while the adrenocortical structure and cholesterol ester storage was compromised, remains to be investigated
It can be high blood pressure, high blood fat levels, or obstructive sleep apnoea