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By 100% minus cause-specific mortality of 17% at 5 yr, as given by "Prognostic impact of serum calcitonin and carcinoembryonic antigen doubling-times in patients with medullary thyroid carcinoma"

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exhibited the cytotoxic effect of zinc oxide (ZnO) nanocrystals in combination with high-energy ultrasound shock waves, however the role of piezoelectric effect remains unclear in the study [225]