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Diarrhea Occurs in approximately 15-25% of patients

At the full 12mg maintenance dose, the majority experience some degree of nausea during the first few weeks, though this typically fades substantially by weeks 8-12 at that dose level

Medications requiring rapid gastrointestinal absorption for efficacy (e.g., oral contraceptives, antibiotics) should be taken at least 1 hour before exenatide injection

In rodent studies, Reta has been generally well tolerated, with side effects typically limited to those commonly seen with incretin-based therapies, such as transient gastrointestinal symptoms