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They stimulate insulin secretion in pancreatic -cells, but their effects on glucagon production in pancreatic -cells differ: GIP has a glucagonotropic effect during hypoglycemia, and GLP-1 exhibits a glucagonostatic effect during hyperglycemia

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Overview of mechanisms of action of lycopene

(c) 3,4-dihydroxy groups located on the B-ring (denoted 3-4 site), resulting in a coordination similar to the catechol mode