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Mechanisms of drug resistance in ovarian cancer and associated gene targets

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Arch Gynecol Obstet 2013;288(6):1405-11

Brayden DJ, Hill TA, Fairlie DP, Maher S, Mrsny RJ

Recently, it was shown that recombinant human GSTs, in particular GSTP1, significantly contributed to the inactivation of AQ-derived QIs by catalyzing GSH-conjugation (Zhang et al., 2017a) ( Figure 1 )