After two rounds of selection, gene deletions were confirmed by PCR on genomic DNA using primers binding ~400 base pairs up- and down-stream of the gene of interest
Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity
For existing spasms, slow, sustained stretching held for 3060 seconds is more effective than ballistic (bouncing) stretches
Source parameters were set as follows: spray voltage 3 kV, capillary temperature 300 C, heater temperature 300 C, sheath gas 50, sweep gas 5, S-lens RF 60, in-source CID 5 eV, microscans 1, automatic gain control target 1e6, and maximum ion time 100 ms
what they care about is, is this going to be profitable for Big Pharma, said Turnock